Methyl 3-chloro-2-oxo-3-phenylpropanoate → HCID 66844968, compound

Reaction equation

[CH3:1][O:2][C:3](=[O:14])[C:4](=O)[CH:5](Cl)[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.[CH:15]1([C:18](=[S:20])[NH2:19])[CH2:17][CH2:16]1>>[CH3:1][O:2][C:3]([C:4]1[N:19]=[C:18]([CH:15]2[CH2:17][CH2:16]2)[S:20][C:5]=1[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)=[O:14]

Participants

Reactant 2

HCID 11769817Methyl 3-chloro-2-oxo-3-phenylpropanoate

HCID 22140884Cyclopropanecarbothioamide

Product 1

HCID 66844968HCID 66844968, compound

Procedure

prepared by reaction of 3-Chloro-2-oxo-3-phenyl-propionic acid methyl ester with cyclopropanecarbothioic acid amide. LC-MS: tR=0.99 min; [M+H]+=260.5.

Sources & evidence

ORD record: ord-57c1f3d9ef1d427291f49bcf952a6189
Source dataset: uspto-grants-2012_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08288429B2

Reaction notes

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