Imidazo[2,1-b][1,3]thiazole-5-carboxylic acid → HCID 86653660, compound

HRID 2064869

Reaction equation

HRID 2064869 reaction equation
[NH2:1][C:2]1[S:3][C:4]([C:17]2[CH:22]=[CH:21][CH:20]=[C:19]([F:23])[CH:18]=2)=[C:5]([C:7]([N:9]2[C@H:14]([CH2:15][NH2:16])[CH2:13][C@H:12]3[C@@H:10]2[CH2:11]3)=[O:8])[N:6]=1.[S:24]1[CH:28]=[CH:27][N:26]2[C:29]([C:32](O)=[O:33])=[CH:30][N:31]=[C:25]12>>[NH2:1][C:2]1[S:3][C:4]([C:17]2[CH:22]=[CH:21][CH:20]=[C:19]([F:23])[CH:18]=2)=[C:5]([C:7]([N:9]2[C@H:14]([CH2:15][NH:16][C:32]([C:29]3[N:26]4[C:25]([S:24][CH:28]=[CH:27]4)=[N:31][CH:30]=3)=[O:33])[CH2:13][C@H:12]3[C@@H:10]2[CH2:11]3)=[O:8])[N:6]=1

Participants

3

Reactant 2

HCID 52983818Imidazo[2,1-b][1,3]thiazole-5-carboxylic acidHCID 86653658[2-amino-5-(3-fluoro-phenyl)-thiazol-4-yl]-((1S,3S,5S)-3-aminomethyl-2-aza-bicyclo[3.1.0]hex-2-yl)-methanone

Product 1

HCID 86653660HCID 86653660, compound

Procedure

prepared by reaction of [2-amino-5-(3-fluoro-phenyl)-thiazol-4-yl]-((1S,3S,5S)-3-aminomethyl-2-aza-bicyclo[3.1.0]hex-2-yl)-methanone with imidazo[2,1-b]thiazole-5-carboxylic acid. LC-MS (basic): tR=0.74 min; [M+H]+=483.0.

Sources & evidence

ORD record
ord-cfabbb8bffb444b4bd480c586ef4ca12
Source dataset
uspto-grants-2012_10
Patent number
US08288435B2

Linked notes

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