HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4-fluorocinnamic acid → (E)-N-[1-(5-Acetyl-furan-2-ylmethyl)-1H-pyrazol-3-yl]-3-(2-chloro-4-fluoro-phenyl)-acrylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4-fluorocinnamic acid | HCID 6257297 | — |
| Reactant | 1-[5-(2-Methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-3-ylamine | HCID 66928781 | — |
| Product | (E)-N-[1-(5-Acetyl-furan-2-ylmethyl)-1H-pyrazol-3-yl]-3-(2-chloro-4-fluoro-phenyl)-acrylamide | HCID 42644402 | — |
Reaction Steps
Following general procedure B followed by either C or D, starting from 1-[5-(2-methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-3-ylamine and (E)-3-(2-chloro-4-fluoro-phenyl)-acrylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288419B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-79562a12231e4cba9b8e95c00bcef98f |
| Source note | uspto-grants-2012_10 |