2-(Trifluoromethyl)cinnamic acid, (E)- → HCID 66929226, compound

HRID 2065167

Reaction equation

HRID 2065167 reaction equation
[CH3:1][C:2]1([CH2:7][CH2:8][CH2:9][CH2:10][N:11]2[CH:15]=[C:14]([NH2:16])[CH:13]=[N:12]2)[O:6]CCO1.[F:17][C:18]([F:31])([F:30])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1/[CH:25]=[CH:26]/[C:27](O)=[O:28]>>[O:6]=[C:2]([CH3:1])[CH2:7][CH2:8][CH2:9][CH2:10][N:11]1[CH:15]=[C:14]([NH:16][C:27](=[O:28])/[CH:26]=[CH:25]/[C:20]2[CH:21]=[CH:22][CH:23]=[CH:24][C:19]=2[C:18]([F:30])([F:31])[F:17])[CH:13]=[N:12]1

Participants

3

Reactant 2

HCID 7196252-(Trifluoromethyl)cinnamic acid, (E)-HCID 669287261-[4-(2-Methyl-[1,3]dioxolan-2-yl)-butyl]-1H-pyrazol-4-ylamine

Product 1

HCID 66929226HCID 66929226, compound

Procedure

Following general procedure B followed by either C or D, starting from 1-[4-(2-methyl-[1,3]dioxolan-2-yl)-butyl]-1H-pyrazol-4-ylamine and (E)-3-(2-trifluoromethyl-phenyl)-acrylic acid.

Sources & evidence

ORD record
ord-c59b9b535fa74eb0aa66fc74d0c56a86
Source dataset
uspto-grants-2012_10
Patent number
US08288419B2

Linked notes

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