Cinnamic Acid → (E)-N-[1-(5-Oxo-hexyl)-1H-pyrazol-3-yl]-3-phenyl-acrylamide

HRID 2065176

Reaction equation

HRID 2065176 reaction equation
[CH3:1][C:2]1([CH2:7][CH2:8][CH2:9][CH2:10][N:11]2[CH:15]=[CH:14][C:13]([NH2:16])=[N:12]2)[O:6]CCO1.[C:17]1(/[CH:23]=[CH:24]/[C:25](O)=[O:26])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[O:6]=[C:2]([CH3:1])[CH2:7][CH2:8][CH2:9][CH2:10][N:11]1[CH:15]=[CH:14][C:13]([NH:16][C:25](=[O:26])/[CH:24]=[CH:23]/[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[N:12]1

Participants

3

Reactant 2

HCID 444539Cinnamic AcidHCID 669284811-[4-(2-Methyl-[1,3]dioxolan-2-yl)-butyl]-1H-pyrazol-3-ylamine

Product 1

HCID 66928817(E)-N-[1-(5-Oxo-hexyl)-1H-pyrazol-3-yl]-3-phenyl-acrylamide

Procedure

Following general procedure B followed by either C or D, starting from 1-[4-(2-methyl-[1,3]dioxolan-2-yl)-butyl]-1H-pyrazol-3-ylamine and (E)-3-phenyl-acrylic acid.

Sources & evidence

ORD record
ord-bb12be055d4746e8b8e22ffdc6d3c875
Source dataset
uspto-grants-2012_10
Patent number
US08288419B2

Linked notes

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