4-Piperidinone, 2,2,6,6-tetramethyl-, monohydrate → 1,3-Bis[(2,2,6,6-tetramethylpiperidin-4-ylidene)amino]guanidine;hydrochloride

HRID 2071226

Reaction equation

[ClH:1].[NH2:2][NH:3][C:4](=[NH:7])[NH:5][NH2:6].O.[CH3:9][C:10]1([CH3:19])[CH2:15][C:14](=O)[CH2:13][C:12]([CH3:18])([CH3:17])[NH:11]1>C(O)C>[ClH:1].[CH3:9][C:10]1([CH3:19])[CH2:15][C:14](=[N:2][NH:3][C:4]([NH:5][N:6]=[C:14]2[CH2:13][C:12]([CH3:18])([CH3:17])[NH:11][C:10]([CH3:19])([CH3:9])[CH2:15]2)=[NH:7])[CH2:13][C:12]([CH3:18])([CH3:17])[NH:11]1

Participants

Conditions

Temperature: 25 °C

Procedure

A solution of diaminoguanidine hydrochloride (6.28 grams; 0.05 mole) and 2,2,6,6-tetramethyl-4-piperidone monohydrate (17.3 grams; 0.10 mole) in 200 mls. of ethanol 2B was refluxed for a period of 15 hours while stirring. The resulting slurry was cooled to 25° C. and the solid was separated to obtain 10.0 grams of crude 1,3-bis[(2,2,6,6-tetramethyl-4-piperidylidene)amino]guanidine hydrochloride. Recrystallization of the crude hydrochloride from ethanol 2B gave 8.9 grams of white solid, m.p. 210°-220° C. (dec).

Workup

customthe solid was separated

Sources & evidence

ORD record: ord-1e13c509264d44a7bd1bc31b5f3b60ab
Source dataset: uspto-grants-1977_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04046736

Linked notes

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