Thionyl Chloride → HCID 178443472, compound

Reaction equation

[CH2:1]([C@H:9]1[CH2:14][CH2:13][C@H:12]([C:15]([OH:17])=O)[CH2:11][CH2:10]1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].S(Cl)([Cl:20])=O>>[CH2:1]([C@H:9]1[CH2:14][CH2:13][C@H:12]([C:15]([Cl:20])=[O:17])[CH2:11][CH2:10]1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

Reactant 2

HCID 24386Thionyl Chloride2×

HCID 178443474HCID 178443474, compound

Product 1

HCID 178443472HCID 178443472, compound

Conditions

Temperature: 60 °C

Procedure

1.16 g (4.82 mM) of trans-4-n-octylcyclohexane-carboxylic acid was added to thionyl chloride, and the mixture was heated at 60° C. for 3 hours, followed by distilling-off of an excess of the thionyl chloride, to obtain 1.00 g (3.86 mM) of trans-4-n-octylcyclohexane-carboxylic acid chloride.

Sources & evidence

ORD record: ord-e6c4087114fa4d54a3a72f888ea84ae6
Source dataset: uspto-grants-1990_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04917821

Reaction notes

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