Reaction equation
[CH3:1][CH:2]([CH3:16])[CH2:3][CH2:4][O:5][CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([N+:13]([O-])=O)[CH:8]=1>ClCCl>[CH3:1][CH:2]([CH3:16])[CH2:3][CH2:4][O:5][CH2:6][C:7]1[CH:8]=[C:9]([CH:10]=[CH:11][CH:12]=1)[NH2:13]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
After condensing the filtrate together with the ethanol washings, the condensate was dissolved into 300 ml of dichloromethane and after washing the thus formed solution with an aqueous 10% sodium carbonate solution, then with an aqueous saturated sodium chloride solution, the thus washed solution was dried over anhydrous potassium carbonate. By distilling the solvent off from the thus dried solution and fractionally distilling the residue, 109.2 g of a fraction boiling at 105° to 106° C. (0.19 mmHg) were collected to obtain 3-[(3-methylbutoxy)methyl]aniline in a yield of 97.1%.
Workup
- washafter washing the thus formed solution with an aqueous 10% sodium carbonate solution
- dry with materialwith an aqueous saturated sodium chloride solution, the thus washed solution was dried over anhydrous potassium carbonate
- distillationBy distilling the solvent off from the thus dried solution
- distillationfractionally distilling the residue, 109.2 g of a fraction boiling at 105° to 106° C. (0.19 mmHg)
- customwere collected
Sources & evidence
- ORD record
- ord-9fc733f94c024e5bb2976bcf7767e8ad
- Source dataset
- uspto-grants-1990_04
- Patent number
- US04919707
Linked notes
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