Boronic acid, (4-ethylphenyl)- → N-(5-(4-ethylphenyl)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)nicotinamide

HRID 207447

Reaction equation

HRID 207447 reaction equation
[Br:1][c:2]1[cH:3][c:4]([NH:14][C:15]([c:16]2[cH:17][n:18][cH:19][cH:20][cH:21]2)=[O:22])[cH:5][n:6][c:7]1[O:8][CH2:9][C:10]([F:11])([F:12])[F:13].[CH2:23]([CH3:24])[c:25]1[cH:26][cH:27][c:28]([B:31]([OH:32])[OH:33])[cH:29][cH:30]1>>[c:2]1(-[c:28]2[cH:27][cH:26][c:25]([CH2:23][CH3:24])[cH:30][cH:29]2)[cH:3][c:4]([NH:14][C:15]([c:16]2[cH:17][n:18][cH:19][cH:20][cH:21]2)=[O:22])[cH:5][n:6][c:7]1[O:8][CH2:9][C:10]([F:11])([F:12])[F:13]

Participants

3

Reactant 2

HCID 2734352Boronic acid, (4-ethylphenyl)-HCID 67280716N-(5-bromo-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)nicotinamide

Product 1

HCID 56961394N-(5-(4-ethylphenyl)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)nicotinamide

Sources & evidence

ORD record
ord-aa9efea83f0d4e75b96b8ffca267651a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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