3,5-Bis-trifluoromethylphenylboronic acid → 1-({5-[3,5-bis(Trifluoromethyl)phenyl]-2-furanyl}methyl)-2-cyclopropyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

HRID 208111

Reaction equation

HRID 208111 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:7][n:8]2[c:9]([CH:23]3[CH2:24][CH2:25]3)[cH:10][c:11]3[c:12]([C:19]([F:20])([F:21])[F:22])[c:13]([C:17]#[N:18])[cH:14][cH:15][c:16]23)[o:6]1.[F:26][C:27]([c:28]1[cH:29][c:30]([B:38]([OH:39])[OH:40])[cH:31][c:32]([C:34]([F:35])([F:36])[F:37])[cH:33]1)([F:41])[F:42]>>[c:2]1(-[c:30]2[cH:29][c:28]([C:27]([F:26])([F:41])[F:42])[cH:33][c:32]([C:34]([F:35])([F:36])[F:37])[cH:31]2)[cH:3][cH:4][c:5]([CH2:7][n:8]2[c:9]([CH:23]3[CH2:24][CH2:25]3)[cH:10][c:11]3[c:12]([C:19]([F:20])([F:21])[F:22])[c:13]([C:17]#[N:18])[cH:14][cH:15][c:16]23)[o:6]1

Participants

3

Reactant 2

HCID 1562653,5-Bis-trifluoromethylphenylboronic acidHCID 674049931-[(5-Bromo-2-furanyl)methyl]-2-cyclopropyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

Product 1

HCID 866207151-({5-[3,5-bis(Trifluoromethyl)phenyl]-2-furanyl}methyl)-2-cyclopropyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

Sources & evidence

ORD record
ord-518fd4490cad490d9cedcae34b9ed8da
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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