3-Butylamino-4-phenoxy-5-sulphamyl-benzamide → (4-Benzyl-3-n-butoxy-5-sulfamylbenzyl)dimethylamine
Reaction equation
C(NC1C=C(C=C(S(=O)(=O)N)C=1OC1C=CC=CC=1)C(N)=O)CCC.[CH2:26]([C:33]1[C:43]([S:44](=[O:47])(=[O:46])[NH2:45])=[CH:42][C:36]([C:37]([N:39]([CH3:41])[CH3:40])=O)=[CH:35][C:34]=1[O:48][CH2:49][CH2:50][CH2:51][CH3:52])[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>>[CH2:26]([C:33]1[C:43]([S:44](=[O:46])(=[O:47])[NH2:45])=[CH:42][C:36]([CH2:37][N:39]([CH3:41])[CH3:40])=[CH:35][C:34]=1[O:48][CH2:49][CH2:50][CH2:51][CH3:52])[C:27]1[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=1Participants
3
Procedure
By replacing in Example 289 3-n-butylamino-4-phenoxy-5-sulfamylbenzamide with an equimolar amount of 4-benzyl-3-n-butoxy-5-sulfamyl-N,N-dimethylbenzamide and following the procedure described, (4-benzyl-3-n-butoxy-5-sulfamylbenzyl)dimethylamine is obtained with a melting point of 110°-111° C. The material (IR, analysis) is identical with the material prepared as in Example 180.
Sources & evidence
- ORD record
- ord-b414f6e9c1c649e78b8de07c0bed9ae5
- Source dataset