Cyclopentanone → Cyclohexanone, 2-[(2-oxocyclopentyl)methyl]-

HRID 2083222

Reaction equation

CN([CH2:4][CH:5]1[CH2:10][CH2:9][CH2:8][CH2:7][C:6]1=[O:11])C.[C:12]1(=[O:17])[CH2:16][CH2:15][CH2:14][CH2:13]1>>[O:17]=[C:12]1[CH2:16][CH2:15][CH2:14][CH:13]1[CH2:4][CH:5]1[CH2:10][CH2:9][CH2:8][CH2:7][C:6]1=[O:11]

Participants

Reactant 2

HCID 8452Cyclopentanone

HCID 858382-((Dimethylamino)methyl)cyclohexanone

Product 1

HCID 4738124Cyclohexanone, 2-[(2-oxocyclopentyl)methyl]-Yield 80%

Procedure

2-(2'-Oxocyclopentyl)methyl cyclohexanone was prepared from 2-(dimethylaminomethyl)cyclohexanone and cyclopentanone according to the method described in Ann. Chim. 1963, 53 (6), 819 and was isolated as a colourless oil in 80% yield b.p. 92°/0.05 mm.

Sources & evidence

ORD record: ord-8b4e46c462534ac6a99d13210dfa7870
Source dataset: uspto-grants-1978_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04085108

Linked notes

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