(3R)-(+)-3-(tert-Butoxycarbonylamino)pyrrolidine → 8-phenyl-4-((4aR,7aR)-tetrahydro-1H-pyrrolo[3,4-b]pyridin-6(2H,7H,7aH)-yl)-5,6,7,8-tetrahydroquinazolin-2-amine
Reaction equation
CC1C=CC(S(O[C:12]2[C:13]3[CH2:23][CH2:22][CH2:21][CH2:20][C:19]([CH3:25])([CH3:24])[C:14]=3[N:15]=[C:16]([NH2:18])[N:17]=2)(=O)=O)=CC=1.[N:26]1(C(OC(C)(C)C)=O)[CH2:31][CH2:30][CH2:29][C@@H:28]2[CH2:32][NH:33][CH2:34][C@H:27]12.N1C[CH2:45][C@@H:44](NC(=O)OC(C)(C)C)[CH2:43]1>>[C:19]1([CH:20]2[C:12]3[N:17]=[C:16]([NH2:18])[N:15]=[C:14]([N:33]4[CH2:32][C@@H:28]5[C@@H:27]([NH:26][CH2:31][CH2:30][CH2:29]5)[CH2:34]4)[C:13]=3[CH2:23][CH2:22][CH2:21]2)[CH:24]=[CH:45][CH:44]=[CH:43][CH:25]=1Participants
4
