Dimethyl Sulfoxide → 3-Bromo-2,5-difluorophenylacetonitrile

Reaction equation

[Br:1][c:2]1[c:3]([F:11])[c:4]([CH2:9][Cl:10])[cH:5][c:6]([F:8])[cH:7]1.[CH3:15][S:16](=[O:17])[CH3:18].[K:12][C:13]#[N:14]>>[Br:1][c:2]1[c:3]([F:11])[c:4]([CH2:9][C:13]#[N:14])[cH:5][c:6]([F:8])[cH:7]1

Participants

Reactant 3

HCID 679Dimethyl Sulfoxide

HCID 666575721-Bromo-3-(chloromethyl)-2,5-difluorobenzene

HCID 178511842HCID 178511842, compound

Product 1

HCID 666575683-Bromo-2,5-difluorophenylacetonitrile

Sources & evidence

ORD record: ord-4a77ed07bbff4c91b0e27e02a132b33f
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…