3-Chloro-2-(3-cyclopropoxy-4-difluoromethoxyphenyl)-1-(2-trimethylsilylethoxymethyl)-1,5-dihydropyrrolo[2,3-d]pyridazin-4-one → 2-(8-Difluoromethoxy-2,2-dimethyl-2H-chromen-5-yl)-3-methyl-1,5-dihydropyrrolo[2,3-d]pyridazin-4-one HCl

Reaction equation

[F:1][CH:2]([F:35])[O:3][C:4]1[CH:5]=[CH:6][C:7]([C:16]2[NH:33][C:19]3[CH:20]=[N:21][N:22](COCC[Si](C)(C)C)[C:23](=[O:24])[C:18]=3[C:17]=2[CH3:34])=[C:8]2[C:13]=1[O:12][C:11]([CH3:15])([CH3:14])[CH:10]=[CH:9]2.[Cl:36]C1C2C(=O)NN=CC=2N(COCC[Si](C)(C)C)C=1C1C=CC(OC(F)F)=C(OC2CC2)C=1>>[ClH:36].[F:35][CH:2]([F:1])[O:3][C:4]1[CH:5]=[CH:6][C:7]([C:16]2[NH:33][C:19]3[CH:20]=[N:21][NH:22][C:23](=[O:24])[C:18]=3[C:17]=2[CH3:34])=[C:8]2[C:13]=1[O:12][C:11]([CH3:15])([CH3:14])[CH:10]=[CH:9]2