Boron tribromide → 4-{[2-Hydroxy-4,4-dimethyl-5-methoxy-2-trifluoromethyl-1,2,3,4-tetrahydronaphthalen-1-yl]amino}-phthalide
Reaction equation
[B:32]([Br:33])([Br:34])[Br:35].[CH3:1][O:2][c:3]1[c:4]([C:9]([CH2:10][C:11]([CH:12]=[O:13])([C:14]([F:15])([F:16])[F:17])[OH:18])([CH3:19])[CH3:20])[cH:5][cH:6][cH:7][cH:8]1.[NH2:21][c:22]1[c:23]2[c:28]([cH:29][cH:30][cH:31]1)[C:26](=[O:27])[O:25][CH2:24]2>>[CH3:1][O:2][c:3]1[c:4]2[c:5]([cH:6][cH:7][cH:8]1)[CH:12]([NH:21][c:22]1[c:23]3[c:28]([cH:29][cH:30][cH:31]1)[C:26](=[O:27])[O:25][CH2:24]3)[C:11]([C:14]([F:15])([F:16])[F:17])([OH:18])[CH2:10][C:9]2([CH3:19])[CH3:20]Participants
4
Sources & evidence
- ORD record
- ord-b91e769c13e74cc2bc8902e057495d45
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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