Methyl 4-iodobenzoate → 4-(Cyclopropylethynyl)benzoic acid
Reaction equation
[CH:1]1([C:4]#[C:5][C:6]2[CH:14]=[CH:13][C:9]([C:10]([OH:12])=[O:11])=[C:8](C)[CH:7]=2)[CH2:3][CH2:2]1.IC1C=CC(C(OC)=O)=CC=1>>[CH:1]1([C:4]#[C:5][C:6]2[CH:7]=[CH:8][C:9]([C:10]([OH:12])=[O:11])=[CH:13][CH:14]=2)[CH2:2][CH2:3]1Participants
3
Procedure
The above compound was prepared using the same procedure as 4-(cyclopropylethynyl)-2-methylbenzoic acid, except methyl 4-iodobenzoate was used as the starting material.
Workup
- customThe above compound was prepared
Sources & evidence
- ORD record
- ord-494e9dc244c348d99fda7255388aea5c
- Source dataset
- uspto-grants-2009_08
- Patent number
- US07576099B2
Reaction notes
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