Chloroacetyl chloride → 2-chloro-N-(4-chloro-3-nitrophenyl)acetamide

Reaction equation

[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].[Cl:12][CH2:13][C:14](Cl)=[O:15]>>[Cl:12][CH2:13][C:14]([NH:6][C:5]1[CH:7]=[CH:8][C:2]([Cl:1])=[C:3]([N+:9]([O-:11])=[O:10])[CH:4]=1)=[O:15]

Participants

Reactant 2

HCID 6577Chloroacetyl chloride

HCID 124774-Chloro-3-nitroaniline

Product 1

HCID 20606032-chloro-N-(4-chloro-3-nitrophenyl)acetamide

Procedure

The method described in Referential Example 502 was performed by use of 4-chloro-3-nitroaniline and chloroacetyl chloride, whereby the title compound was obtained.

Sources & evidence

ORD record: ord-689d8097094b44caa2b2cf78ff4f278c
Source dataset: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07576135B2

Reaction notes

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