3-Mercaptophenylboronic Acid → 3-(4-Carboxymethyl-benzylsulfanyl)phenylboronic acid
Reaction equation
Br[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10]([OH:12])=[O:11])=[CH:5][CH:4]=1.[SH:13][C:14]1[CH:15]=[C:16]([B:20]([OH:22])[OH:21])[CH:17]=[CH:18][CH:19]=1>>[C:10]([CH2:9][C:6]1[CH:7]=[CH:8][C:3]([CH2:2][S:13][C:14]2[CH:15]=[C:16]([B:20]([OH:22])[OH:21])[CH:17]=[CH:18][CH:19]=2)=[CH:4][CH:5]=1)([OH:12])=[O:11]Participants
3
Procedure
3-(4-Carboxymethyl-benzylsulfanyl)phenylboronic acid was prepared from 4-(bromomethyl)phenyl acetic acid and 3-mecaptophenylboronic acid according to the procedure of Example 41.
Sources & evidence
- ORD record
- ord-782308d696a9496ca12bf618bb4800c5
- Source dataset
- uspto-grants-2009_08
- Patent number
- US07576215B2
Reaction notes
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