2-Benzofurancarboxaldehyde → N-(1-benzofuran-2-ylmethyl)-3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]aniline

HRID 2104854

Reaction equation

HRID 2104854 reaction equation
[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH2:24])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:27])[F:26])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[O:29]1[C:33]2[CH:34]=[CH:35][CH:36]=[CH:37][C:32]=2[CH:31]=[C:30]1[CH:38]=O>>[O:29]1[C:33]2[CH:34]=[CH:35][CH:36]=[CH:37][C:32]=2[CH:31]=[C:30]1[CH2:38][NH:24][C:20]1[CH:21]=[CH:22][CH:23]=[C:18]([C:17]2[C:16]3[C:11](=[C:12]([C:25]([F:28])([F:26])[F:27])[CH:13]=[CH:14][CH:15]=3)[N:10]=[CH:9][C:8]=2[CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH:19]=1

Participants

3

Reactant 2

HCID 613412-BenzofurancarboxaldehydeHCID 112342973-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamine

Product 1

HCID 66914433N-(1-benzofuran-2-ylmethyl)-3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]aniline

Procedure

This compound was prepared according to the procedure of example 66, substituting 3-(3-benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamine and benzofuran-2 carbaldehyde. MS (ESI) m/z 509.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-767d6592ef8f4516b4ce694d468747e0
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Linked notes

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