3-Bromopropionitrile → 3-(Piperazin-1-yl)propanenitrile

HRID 2105863

Reaction equation

C(O[C:6]([N:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)=O)(C)(C)C.BrC[CH2:16][C:17]#[N:18]>>[N:8]1([CH2:6][CH2:16][C:17]#[N:18])[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1

Participants

Reactant 2

HCID 170203-Bromopropionitrile

HCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 20520503-(Piperazin-1-yl)propanenitrile

Procedure

The title compound was prepared from 1-tert-butyloxycarbonyl-piperazine and 3-bromopropionitrile in an analogous manner as described in example 21.

Sources & evidence

ORD record: ord-343c7ea2f42c410b8cc8a9bb8b7c314f
Source dataset: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07579368B2

Linked notes

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