Ethyl bromopyruvate → 4-Thiazolecarboxylic acid, 2-(ethylamino)-, ethyl ester
Reaction equation
[CH2:1]([NH:3][C:4]([NH2:6])=[S:5])[CH3:2].Br[CH2:8][C:9](=O)[C:10]([O:12][CH2:13][CH3:14])=[O:11]>C(O)C>[CH2:1]([NH:3][C:4]1[S:5][CH:8]=[C:9]([C:10]([O:12][CH2:13][CH3:14])=[O:11])[N:6]=1)[CH3:2]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
The reaction described in Preparation 42 was repeated but using 10 g of ethylthiourea, 20 g of ethyl bromopyruvate and 100 ml of ethanol, giving the title compound as a pale yellow powder.
Workup
- customThe reaction described in Preparation 42
Sources & evidence
- ORD record
- ord-5720cd20ce9a47fab55608c988cdc9d7
- Source dataset
- uspto-grants-1990_06
- Patent number
- US04933355
Reaction notes
Loading…