trans-2-(4-Methyl-cyclohexylcarbamoyl)-cyclopropane carboxylic acid → HCID 178455807, compound

HRID 2111697

Reaction equation

HRID 2111697 reaction equation
[CH2:1]([CH:3]1[CH2:8][CH2:7][CH:6]([NH:9][C:10]([C@@H:12]2[CH2:14][C@H:13]2[C:15](O)=[O:16])=[O:11])[CH2:5][CH2:4]1)[CH3:2].CC1CCC(NC([C@@H]2C[C@H]2C(O)=O)=O)CC1>>[CH2:1]([C@H:3]1[CH2:4][CH2:5][C@H:6]([NH:9][C:10]([C@@H:12]2[CH2:14][C@H:13]2[CH2:15][OH:16])=[O:11])[CH2:7][CH2:8]1)[CH3:2]

Participants

3

Reactant 2

HCID 18436993trans-2-(4-Methyl-cyclohexylcarbamoyl)-cyclopropane carboxylic acidHCID 45086924trans-2-(4-Ethyl-cyclohexylcarbamoyl)-cyclopropanecarboxylic acid

Product 1

HCID 178455807HCID 178455807, compound

Procedure

Follow the procedure of Example 11c, and substitute trans-2-(4-ethyl-cyclohexylcarbamoyl)-cyclopropanecarboxylic acid (Example 13b) for trans-2-(4-methyl-cyclohexylcarbamoyl)-cyclopropane carboxylic acid therein to obtain the title compound.

Sources & evidence

ORD record
ord-6cc940018a50416986def5a0adaf4d37
Source dataset
uspto-grants-2009_04
Patent number
US07521445B2

Linked notes

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