4-(4-Chlorophenyl)pyridine → 2-Chloro-4-(4-chlorophenyl)pyridine

HRID 2113546

Reaction equation

HRID 2113546 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][N:11]=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.FC1C=CC(C2C=CN=C([Cl:27])C=2)=CC=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:9]=[CH:10][N:11]=[C:12]([Cl:27])[CH:13]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 3038234-(4-Chlorophenyl)pyridineHCID 231207302-Chloro-4-(4-fluorophenyl)pyridine

Product 1

HCID 231207332-Chloro-4-(4-chlorophenyl)pyridine

Procedure

4-(4-Chlorophenyl)-2-chloropyridine is prepared from 4-(4-chlorophenyl)-pyridine using the same reaction sequence as that described for the preparation of 4-(4-fluorophenyl)-2-chloropyridine (Example 21, steps b and c).

Sources & evidence

ORD record
ord-e4374852b253474994ec93a6a6ae8772
Source dataset
uspto-grants-2008_10
Patent number
US07432269B2

Linked notes

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