Ethanol → Ethyl 6-methyl-1H-pyrrolo[3,2-B]pyridine-3-carboxylate

Reaction equation

[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][n:8]([OH:16])[c:9]2[c:10]1[n:11][cH:12][c:13]([CH3:15])[cH:14]2.[CH3:17][CH2:18][OH:19].[OH-:20].[OH-:21].[Pd+2:22]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][nH:8][c:9]2[c:10]1[n:11][cH:12][c:13]([CH3:15])[cH:14]2

Participants

Reactant 4

HCID 702Ethanol

HCID 961Hydroxide2×

HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

HCID 600601751-Hydroxy-6-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxylic acid ethyl ester

Product 1

HCID 60060164Ethyl 6-methyl-1H-pyrrolo[3,2-B]pyridine-3-carboxylate

Sources & evidence

ORD record: ord-b712269f5b29488bb3c54332204e14af
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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