HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Phenylethyl)piperidine → 2-Oxo-N-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-7-yl)-2-(4-phenethyl-piperidin-1-yl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Phenylethyl)piperidine | HCID 4341895 | — |
| Reactant | N-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-7-yl)-oxalamic acid | HCID 69100554 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 2-Oxo-N-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-7-yl)-2-(4-phenethyl-piperidin-1-yl)-acetamide | HCID 69100259 | — |
Reaction Steps
The title compound is prepared from N-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-7-yl)-oxalamic acid (Example 53b) and 4-phenethyl-piperidine [J. Amer. Chem. Soc., 72, 4953. (1950)] according to the method described in Example 1c. Melting Point: 128-132° C. (diethylether)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07435744B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-8da8834830fe49d3ac158fb98d2c50c2 |
| Source note | uspto-grants-2008_10 |