Benzo(b)thiophene-2-carboxylic acid → N-[3-cyano-4-(4-(2-hydroxyethyl)piperazin-1-yl)phenyl]benzo[b]thiophene-2-carboxamide
Reaction equation
[NH2:13][c:14]1[cH:15][cH:16][c:17]([N:22]2[CH2:23][CH2:24][N:25]([CH2:28][CH2:29][OH:30])[CH2:26][CH2:27]2)[c:18]([C:19]#[N:20])[cH:21]1.[s:1]1[c:2]2[c:3]([cH:4][c:5]1[C:6](=[O:7])[OH:8])[cH:9][cH:10][cH:11][cH:12]2>>[s:1]1[c:2]2[c:3]([cH:4][c:5]1[C:6](=[O:8])[NH:13][c:14]1[cH:15][cH:16][c:17]([N:22]3[CH2:23][CH2:24][N:25]([CH2:28][CH2:29][OH:30])[CH2:26][CH2:27]3)[c:18]([C:19]#[N:20])[cH:21]1)[cH:9][cH:10][cH:11][cH:12]2Participants
3
Sources & evidence
- ORD record
- ord-5235c8010e574675b55e916c48b72b9e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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