1-Bromoisoquinoline → 1-Bromo-2-methylisoquinolinium tetrafluoroborate
Reaction equation
[Br:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][N:3]=1.[F:12][B-:13]([F:16])([F:15])[F:14].[CH3:17][O+](C)C>C(Cl)Cl>[F:12][B-:13]([F:16])([F:15])[F:14].[Br:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][N+:3]=1[CH3:17]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
The starting material was prepared by reaction of 1-bromoisoquinoline with trimethyloxonium tetrafluoroborate in CH2Cl2 to give 1-bromo-2-methylisoquinolinium tetrafluoroborate, m.p. 162°.
Sources & evidence
- ORD record
- ord-ac0fd97dbf8d414f8bd35fe6df3a2149
- Source dataset
- uspto-grants-1987_07
- Patent number
- US04678781
Reaction notes
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