4-[(4-fluorophenyl)amino]-1-methyl-1H-pyrazole-5-carboxylic acid → 9H-Pyrazolo[4,3-b]quinolin-9-one, 7-ethyl-1,4-dihydro-1-methyl-

HRID 2119619

Reaction equation

HRID 2119619 reaction equation
[CH2:1]([C:3]1[CH:8]=[CH:7][C:6]([NH:9][C:10]2[CH:11]=[N:12][N:13]([CH3:18])[C:14]=2[C:15]([OH:17])=O)=[CH:5][CH:4]=1)[CH3:2].FC1C=CC(NC2C=NN(C)C=2C(O)=O)=CC=1>>[CH2:1]([C:3]1[CH:4]=[CH:5][C:6]2[NH:9][C:10]3[CH:11]=[N:12][N:13]([CH3:18])[C:14]=3[C:15](=[O:17])[C:7]=2[CH:8]=1)[CH3:2]

Participants

3

Reactant 2

HCID 129856934-[(4-fluorophenyl)amino]-1-methyl-1H-pyrazole-5-carboxylic acidHCID 129857044-[(4-ethylphenyl)amino]-1-methyl-1H-pyrazole-5-carboxylic acid

Product 1

HCID 129857059H-Pyrazolo[4,3-b]quinolin-9-one, 7-ethyl-1,4-dihydro-1-methyl-

Procedure

The title compound was prepared according to the procedure of step 2 in EXAMPLE 1 using 4-[(4-ethylphenyl)amino]-1-methyl-1H-pyrazole-5-carboxylic acid (EXAMPLE 6, step 1), instead of 4-[(4-fluorophenyl)amino]-1-methyl-1H-pyrazole-5-carboxylic acid.

Sources & evidence

ORD record
ord-15dbdd85974c44e89b3a3ddfe0f2e59c
Source dataset
uspto-grants-2004_02
Patent number
US06686373B2

Linked notes

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