1,2-Diaminocyclohexane, trans- → (R,R)-N,N'-Bis[4-(N-ethyl-N-methylamino)salicylidene]-1,2-cyclohexanediamine
Reaction equation
[CH2:1]([N:3]([C:5]1[CH:6]=[C:7]([OH:13])[C:8](=[CH:11][CH:12]=1)[CH:9]=O)[CH3:4])[CH3:2].[C@@H:14]1([NH2:21])[CH2:19][CH2:18][CH2:17][CH2:16][C@H:15]1[NH2:20]>>[CH2:1]([N:3]([C:5]1[CH:6]=[C:7]([OH:13])[C:8](=[CH:11][CH:12]=1)[CH:9]=[N:20][C@@H:15]1[CH2:16][CH2:17][CH2:18][CH2:19][C@H:14]1[N:21]=[CH:9][C:8]1[C:7](=[CH:6][C:5]([N:3]([CH3:4])[CH2:1][CH3:2])=[CH:12][CH:11]=1)[OH:13])[CH3:4])[CH3:2]Participants
3
Procedure
Synthesis and working up are carried out as in Example 9, starting from 500 mg (2.79 mmol) of 4-(N-ethyl-N-methylamino)salicylaldehyde and 152 mg (1.33 mmol) of trans-1,2-cyclohexanediamine. Yield: 569 mg (98%), yellow solid.
Workup
- customSynthesis
Sources & evidence
- ORD record
- ord-908bcd9dad83499a878583cf4a08d6bb