1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperidine → (1-Methyl-cyclohexyl)-[2-(4-piperidin-1-yl-phenyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-methanone

HRID 2124318Notes

Reaction equation

HRID 2124318 reaction equation
[Br:1][c:2]1[n:3][c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][c:10]2[C:11](=[O:12])[C:13]1([CH3:19])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18]1.[CH3:20][C:21]1([CH3:22])[C:23]([CH3:24])([CH3:25])[O:26][B:27]([c:28]2[cH:29][cH:30][c:31]([N:34]3[CH2:35][CH2:36][CH2:37][CH2:38][CH2:39]3)[cH:32][cH:33]2)[O:40]1>>[c:2]1(-[c:28]2[cH:29][cH:30][c:31]([N:34]3[CH2:35][CH2:36][CH2:37][CH2:38][CH2:39]3)[cH:32][cH:33]2)[n:3][c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][c:10]2[C:11](=[O:12])[C:13]1([CH3:19])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18]1

Participants

3

Reactant 2

HCID 49612501-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperidineHCID 44199730(2-bromo-5H-pyrrolo[2,3-b]pyrazin-7-yl)-(1-methyl-cyclohexyl)-methanone

Product 1

HCID 59541069(1-Methyl-cyclohexyl)-[2-(4-piperidin-1-yl-phenyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-methanone

Sources & evidence

ORD record
ord-5f73ebec4c0342318eb1342b5e60c676
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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