Potassium Cation → tert-butyl 4-[(4-oxopiperidin-1-yl)methyl]tetrahydro-2H-pyran-4-carboxylate

Reaction equation

[CH2:23]([N+:24]1([CH3:25])[CH2:26][CH2:27][C:28](=[O:31])[CH2:29][CH2:30]1)[CH3:32].[I-:22].[K+:16].[K+:17].[NH2:1][CH2:2][C:3]1([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:4][CH2:5][O:6][CH2:7][CH2:8]1.[O-:18][C:19]([O-:20])=[O:21]>>[N:1]1([CH2:2][C:3]2([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:4][CH2:5][O:6][CH2:7][CH2:8]2)[CH2:26][CH2:27][C:28](=[O:31])[CH2:29][CH2:30]1

Participants

Reactant 5

HCID 813Potassium Cation2×

HCID 19660Carbonate Ion

HCID 30165Iodide Ion

HCID 11097569N-ethyl-N-methyl-4-oxo-piperidinium

HCID 67232834Tert-butyl 4-(aminomethyl)oxane-4-carboxylate

Product 1

HCID 67233968tert-butyl 4-[(4-oxopiperidin-1-yl)methyl]tetrahydro-2H-pyran-4-carboxylate

Sources & evidence

ORD record: ord-e747a533769c4296a4d365a688312970
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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