1-(2,6-Dichlorobenzyl)-7-iodo-3,4-dihydro-1H-pyrido[2,3-b]pyrazin-2-one → 1-(2,6-Dichlorobenzyl)-7-[4-(4-(pyrrolidin-1-yl)piperidine-1-carbonyl)phenyl]-3,4-dihydro-1H-pyrido[2,3-b]pyrazin-2-one
Reaction equation
[Cl:1][c:2]1[c:3]([CH2:4][N:5]2[c:6]3[c:7]([n:12][cH:13][c:14]([I:16])[cH:15]3)[NH:8][CH2:9][C:10]2=[O:11])[c:17]([Cl:21])[cH:18][cH:19][cH:20]1.[N:22]1([CH:27]2[CH2:28][CH2:29][N:30]([C:33](=[O:34])[c:35]3[cH:36][cH:37][c:38]([B:41]4[O:42][C:43]([CH3:44])([CH3:45])[C:46]([CH3:47])([CH3:48])[O:49]4)[cH:39][cH:40]3)[CH2:31][CH2:32]2)[CH2:23][CH2:24][CH2:25][CH2:26]1>>[Cl:1][c:2]1[c:3]([CH2:4][N:5]2[c:6]3[c:7]([n:12][cH:13][c:14](-[c:38]4[cH:37][cH:36][c:35]([C:33]([N:30]5[CH2:29][CH2:28][CH:27]([N:22]6[CH2:23][CH2:24][CH2:25][CH2:26]6)[CH2:32][CH2:31]5)=[O:34])[cH:40][cH:39]4)[cH:15]3)[NH:8][CH2:9][C:10]2=[O:11])[c:17]([Cl:21])[cH:18][cH:19][cH:20]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-000e1b0adaf5438ebbf2a118374b21b7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)