Ethyl 3-((3-(5-(benzylcarbamoyl)-4-methylthiazol-2-yl)-2-oxoimidazolidin-1-yl)methyl)benzoate → 2-(3-(4-Fluorobenzyl)-2-oxoimidazolidin-1-yl)-4-(trifluoromethyl)thiazole-5-carboxylic acid
Reaction equation
[CH2:1]([NH:2][C:3]([c:4]1[s:5][c:6]([N:7]2[CH2:8][CH2:9][N:10]([CH2:11][c:12]3[cH:13][c:14]([C:18]([O:19][CH2:20][CH3:21])=[O:22])[cH:15][cH:16][cH:17]3)[C:23]2=[O:24])[n:25][c:26]1[CH3:27])=[O:28])[c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1.[F:35][c:36]1[cH:37][cH:38][c:39]([CH2:40][N:41]2[C:42](=[O:60])[N:43]([c:46]3[s:47][c:48]([C:55](=[O:56])[O:57][CH2:58][CH3:59])[c:49]([C:51]([F:52])([F:53])[F:54])[n:50]3)[CH2:44][CH2:45]2)[cH:61][cH:62]1>>[F:35][c:36]1[cH:37][cH:38][c:39]([CH2:40][N:41]2[C:42](=[O:60])[N:43]([c:46]3[s:47][c:48]([C:55](=[O:56])[OH:57])[c:49]([C:51]([F:52])([F:53])[F:54])[n:50]3)[CH2:44][CH2:45]2)[cH:61][cH:62]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-c1c667c1d30241fe81711f90ab591242
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)