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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2128302Generated: October 27, 2026

Tetrahydrofuran → methyl 5-amino-5-oxo-4-[3-oxo-7-[[4-(piperidin-1-ylmethyl)phenyl]methoxy]-1H-isoindol-2-yl]pentanoate

https://huagongshe.com/reaction/2128302

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantDiisopropyl diazene-1,2-dicarboxylateHCID 75555—
Reactant4-[(Piperidin-1-yl)methyl]benzyl alcoholHCID 7162041—
ReactantMethyl 5-amino-4-(4-hydroxy-1-oxoisoindolin-2-yl)-5-oxopentanoateHCID 58389139—
Productmethyl 5-amino-5-oxo-4-[3-oxo-7-[[4-(piperidin-1-ylmethyl)phenyl]methoxy]-1H-isoindol-2-yl]pentanoateHCID 67334161—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-c7d80d51739f4a0c90dea24abf42133d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)