Methylhydrazine → 3(2H)-Pyridazinone, 6-(4-chlorophenyl)-4,5-dihydro-2-methyl-

Participants

Reaction Steps

To a 250 ml flask equipped with magnetic stirrer and reflux condenser was charged 10 g of 3-(4-chlorobenzoyl)-propionic acid, 250 ml of absolute ethanol, and 2.5 ml of methyl hydrazine. The reaction was refluxed for 3 hours and cooled to yield a solid which was collected by vacuum filtration, washed with 50 ml of hexane, and air dried. Isolated 9.5 g of product as a white solid.

Provenance & Evidence