tert-Butyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate → 3-[2-(1-t-Butoxycarbonylpyrrolidin-3-ylmethoxy)-4-methylthiobenzoylamino]-N-(5-chloropyridin-2-yl)pyridine-2-carboxamide
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:13][OH:14])[CH2:11][CH2:12]1.[Cl:15][c:16]1[cH:17][cH:18][c:19]([NH:22][C:23](=[O:24])[c:25]2[n:26][cH:27][cH:28][cH:29][c:30]2[NH:31][C:32]([c:33]2[c:34]([OH:40])[cH:35][c:36]([CH3:39])[cH:37][cH:38]2)=[S:41])[n:20][cH:21]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:13][O:14][c:34]2[c:33]([C:32]([NH:31][c:30]3[c:25]([C:23]([NH:22][c:19]4[cH:18][cH:17][c:16]([Cl:15])[cH:21][n:20]4)=[O:24])[n:26][cH:27][cH:28][cH:29]3)=[S:41])[cH:38][cH:37][c:36]([CH3:39])[cH:35]2)[CH2:11][CH2:12]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-d63a8a7a1dee4f7f97619dbde54dc4d3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)