Sodium ion → N-[2-(3,4-dichlorophenyl)ethyl]-2',3'-dihydro-spiro [cyclopropane-1,1'-[1H]indene]-5'-methanamine

HRID 213122

Reaction equation

HRID 213122 reaction equation
[BH4-:49].[CH2:25]1[CH2:26][c:27]2[cH:28][c:29]([CH:36]=[O:37])[cH:30][cH:31][c:32]2[C:33]12[CH2:34][CH2:35]2.[CH:1]1([c:2]2[cH:3][cH:4][c:5]([CH2:6][NH:7][CH2:8][CH2:9][c:10]3[cH:11][cH:12][c:13]([F:14])[c:15]([C:16]([F:17])([F:18])[F:19])[cH:20]3)[cH:21][cH:22]2)[CH2:23][CH2:24]1.[Cl:38][c:39]1[cH:40][c:41]([CH2:46][CH2:47][NH2:48])[cH:42][cH:43][c:44]1[Cl:45].[Na+:50]>>[CH2:25]1[CH2:26][c:27]2[cH:28][c:29]([CH2:36][NH:48][CH2:47][CH2:46][c:41]3[cH:40][c:39]([Cl:38])[c:44]([Cl:45])[cH:43][cH:42]3)[cH:30][cH:31][c:32]2[C:33]12[CH2:34][CH2:35]2

Participants

6

Reactant 5

HCID 923Sodium ionHCID 28123BorohydrideHCID 2179583,4-DichlorophenethylamineHCID 69342889(4-Cyclopropylbenzyl)-[2-(4-fluoro-3-trifluoromethylphenyl)-ethyl]-amineHCID 860938352',3'-Dihydrospiro[cyclopropane-1,1'-indene]-5'-carbaldehyde

Product 1

HCID 69513426N-[2-(3,4-dichlorophenyl)ethyl]-2',3'-dihydro-spiro [cyclopropane-1,1'-[1H]indene]-5'-methanamine

Sources & evidence

ORD record
ord-0c55a50be298491f8c5e96e912de0dde
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

Loading…