2-(7-Amino-8-methoxy-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-acetamide → 2-(7-{5-Chloro-4-[2-methoxy-4-(4-methyl-piperazin-1-yl)-phenylamino]-pyrimidin-2-ylamino}-8-methoxy-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-acetamide
Reaction equation
[Cl:19][c:20]1[n:21][cH:22][c:23]([Cl:42])[c:24]([NH:26][c:27]2[c:28]([O:40][CH3:41])[cH:29][c:30]([N:33]3[CH2:34][CH2:35][N:36]([CH3:39])[CH2:37][CH2:38]3)[cH:31][cH:32]2)[n:25]1.[NH2:1][c:2]1[cH:3][c:4]2[c:5]([cH:15][c:16]1[O:17][CH3:18])[CH2:6][CH2:7][N:8]([CH2:11][C:12](=[O:13])[NH2:14])[CH2:9][CH2:10]2>>[NH:1]([c:2]1[cH:3][c:4]2[c:5]([cH:15][c:16]1[O:17][CH3:18])[CH2:6][CH2:7][N:8]([CH2:11][C:12](=[O:13])[NH2:14])[CH2:9][CH2:10]2)[c:20]1[n:21][cH:22][c:23]([Cl:42])[c:24]([NH:26][c:27]2[c:28]([O:40][CH3:41])[cH:29][c:30]([N:33]3[CH2:34][CH2:35][N:36]([CH3:39])[CH2:37][CH2:38]3)[cH:31][cH:32]2)[n:25]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-5b09dcc157df4ceeb6c44294be30a978
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
- DOI