Ethanol → 5-Bromo-4-ethoxy-6-trifluoromethylpyrimidine

Reaction equation

[Br:5][c:6]1[c:7]([Cl:16])[n:8][cH:9][n:10][c:11]1[C:12]([F:13])([F:14])[F:15].[CH3:17][CH2:18][OH:19].[CH3:2][CH2:3][O-:4].[Na+:1]>>[CH3:2][CH2:3][O:4][c:7]1[c:6]([Br:5])[c:11]([C:12]([F:13])([F:14])[F:15])[n:10][cH:9][n:8]1

Participants

Reactant 4

HCID 702Ethanol

HCID 923Sodium Ion

HCID 1194401-Hydroxyethyl radical

HCID 115362505-Bromo-4-chloro-6-(trifluoromethyl)pyrimidine

Product 1

HCID 178628775-Bromo-4-ethoxy-6-trifluoromethylpyrimidine

Sources & evidence

ORD record: ord-6624aedd3d7745d990e6ff0701fb6283
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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