Dichloromethane → 8-(3-Aminopyrrolidin-1-yl)-7-[(2-iodophenyl)methyl]-1,3-dimethylpurine-2,6-dione

Reaction equation

[Cl:1][c:2]1[n:3][c:4]2[n:5]([CH3:22])[c:6](=[O:21])[n:7]([CH3:20])[c:8](=[O:19])[c:9]2[n:10]1[CH2:11][c:12]1[c:13]([I:18])[cH:14][cH:15][cH:16][cH:17]1.[Cl:29][CH2:30][Cl:31].[NH2:23][CH:24]1[CH2:25][NH:26][CH2:27][CH2:28]1>>[c:2]1([N:26]2[CH2:25][CH:24]([NH2:23])[CH2:28][CH2:27]2)[n:3][c:4]2[n:5]([CH3:22])[c:6](=[O:21])[n:7]([CH3:20])[c:8](=[O:19])[c:9]2[n:10]1[CH2:11][c:12]1[c:13]([I:18])[cH:14][cH:15][cH:16][cH:17]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 1644013-Aminopyrrolidine

HCID 225086268-Chloro-7-(2-iodobenzyl)-1,3-dimethyl-3,7-dihydropurine-2,6-dione

Product 1

HCID 101628238-(3-Aminopyrrolidin-1-yl)-7-[(2-iodophenyl)methyl]-1,3-dimethylpurine-2,6-dione

Sources & evidence

ORD record: ord-1e2fb4ed91674f8f897a53068527ee5c
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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