5-Benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid → 5-benzyloxy-N-(4-isopropylphenyl)-N-[(6-methoxypyridin-3-yl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide

Reaction equation

[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]2[c:15]([cH:16][cH:17][cH:18]1)[CH:14]([C:19](=[O:20])[OH:21])[CH2:13][CH2:12][CH2:11]2.[CH:22]([CH3:23])([CH3:24])[c:25]1[cH:26][cH:27][c:28]([NH:31][CH2:32][c:33]2[cH:34][n:35][c:36]([O:39][CH3:40])[cH:37][cH:38]2)[cH:29][cH:30]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]2[c:15]([cH:16][cH:17][cH:18]1)[CH:14]([C:19](=[O:21])[N:31]([c:28]1[cH:27][cH:26][c:25]([CH:22]([CH3:23])[CH3:24])[cH:30][cH:29]1)[CH2:32][c:33]1[cH:34][n:35][c:36]([O:39][CH3:40])[cH:37][cH:38]1)[CH2:13][CH2:12][CH2:11]2

Participants

Reactant 2

HCID 112083185-Benzyloxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid

HCID 21957879(4-Isopropylphenyl)[(2-methoxy-5-pyridyl)methyl]amine

Product 1

HCID 671843195-benzyloxy-N-(4-isopropylphenyl)-N-[(6-methoxypyridin-3-yl)methyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide

Sources & evidence

ORD record: ord-89503febf85740df904a7efd1e8cd800
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…