Acetic Acid → 2-Methyl-4-methoxy-5-fluoroacetylaminophenol

Reaction equation

[CH3:24][O-:25].[CH3:27][C:28](=[O:29])[OH:30].[CH3:7][c:8]1[c:9]([OH:17])[cH:10][c:11]([NH2:16])[c:12]([O:14][CH3:15])[cH:13]1.[F:18][CH2:19][C:20](=[O:21])[O:22][CH3:23].[Na+:26].[OH2:31].[cH:1]1[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[CH3:7][c:8]1[c:9]([OH:17])[cH:10][c:11]([NH:16][C:20]([CH2:19][F:18])=[O:21])[c:12]([O:14][CH3:15])[cH:13]1

Participants

Reactant 7

HCID 9959Methyl fluoroacetate

HCID 3826051Methoxide

HCID 10197787Phenol, 5-amino-4-methoxy-2-methyl-

Product 1

HCID 198211512-Methyl-4-methoxy-5-fluoroacetylaminophenol

Sources & evidence

ORD record: ord-ea2477310a1f43d29fb36fa3fa417a11
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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