Dimethyl Sulfoxide → 2-[2-Chloro-4-(trifluoromethyl)phenoxy]-5-nitropyridine

Reaction equation

[CH3:30][S:31](=[O:32])[CH3:33].[Cl:19][c:20]1[n:21][cH:22][c:23]([N+:26](=[O:27])[O-:28])[cH:24][cH:25]1.[Cl:7][c:8]1[c:9]([OH:18])[cH:10][cH:11][c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]1.[Na+:1].[Na+:2].[O-:3][C:4](=[O:5])[O-:6].[OH2:29]>>[Cl:7][c:8]1[c:9]([O:18][c:20]2[n:21][cH:22][c:23]([N+:26](=[O:27])[O-:28])[cH:24][cH:25]2)[cH:10][cH:11][c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]1

Participants

Reactant 6

HCID 679Dimethyl Sulfoxide

HCID 923Sodium Ion2×

HCID 962Water

HCID 19660Carbonate Ion

HCID 783082-Chloro-5-nitropyridine

HCID 27366032-Chloro-4-(trifluoromethyl)phenol

Product 1

HCID 133704682-[2-Chloro-4-(trifluoromethyl)phenoxy]-5-nitropyridine

Sources & evidence

ORD record: ord-909dbd5d15e645afb9ca54e0f670d734
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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