3-Methylbenzoyl chloride → [4-(2,4-Diaminoquinazolin-5-yloxymethyl)piperidin-1-yl]-m-tolylmethanone

HRID 214349

Reaction equation

HRID 214349 reaction equation
[NH:1]1[CH2:2][CH2:3][CH:4]([CH2:7][O:8][c:9]2[c:10]3[c:11]([NH2:20])[n:12][c:13]([NH2:19])[n:14][c:15]3[cH:16][cH:17][cH:18]2)[CH2:5][CH2:6]1.[c:21]1([CH3:30])[cH:22][c:23]([C:27](=[O:28])[Cl:29])[cH:24][cH:25][cH:26]1>>[N:1]1([C:27]([c:23]2[cH:22][c:21]([CH3:30])[cH:26][cH:25][cH:24]2)=[O:28])[CH2:2][CH2:3][CH:4]([CH2:7][O:8][c:9]2[c:10]3[c:11]([NH2:20])[n:12][c:13]([NH2:19])[n:14][c:15]3[cH:16][cH:17][cH:18]2)[CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 743753-Methylbenzoyl chlorideHCID 575765655-(Piperidin-4-ylmethoxy)quinazoline-2,4-diamine

Product 1

HCID 25002417[4-(2,4-Diaminoquinazolin-5-yloxymethyl)piperidin-1-yl]-m-tolylmethanone

Sources & evidence

ORD record
ord-ab0edeb14e1c4177970715bedae1fbf2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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