Dichloromethane → Methyl 2-amino-4-bromothiophene-3-carboxylate

Reaction equation

[CH2:32]1[NH:33][CH2:34][CH2:35][O:36][CH2:37]1.[Cl:29][CH2:30][Cl:31].[cH:1]1[c:2]2[c:14]([cH:15][cH:16][cH:17]1)-[c:9]1[c:8]([cH:13][cH:12][cH:11][cH:10]1)[CH:3]2[CH2:4][O:5][C:6](=[O:7])[NH:18][c:19]1[s:20][cH:21][c:22]([Br:28])[c:23]1[C:24](=[O:25])[O:26][CH3:27]>>[NH2:18][c:19]1[s:20][cH:21][c:22]([Br:28])[c:23]1[C:24](=[O:25])[O:26][CH3:27]

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 8083Morpholine

HCID 68756520Methyl 2-((((9h-fluoren-9-yl)methoxy)carbonyl)amino)-4-bromothiophene-3-carboxylate

Product 1

HCID 68754257Methyl 2-amino-4-bromothiophene-3-carboxylate

Sources & evidence

ORD record: ord-912faa08a2424afb8dc0b1ccb7c56c08
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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