Dichloromethane → 4-((5-Chloro-3-methyl-pyridin-2-ylmethyl)-{3-[1-(4-fluoro-phenyl)-1-methyl-ethyl]-pyridin-2-ylmethyl}-amino)-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][CH2:15][c:16]2[n:17][cH:18][cH:19][cH:20][c:21]2[C:22]([CH3:23])([CH3:24])[c:25]2[cH:26][cH:27][c:28]([F:31])[cH:29][cH:30]2)[CH2:12][CH2:13]1.[Cl:32][c:33]1[cH:34][c:35]([CH3:41])[c:36]([CH:39]=[O:40])[n:37][cH:38]1.[Cl:42][CH2:43][Cl:44]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([N:14]([CH2:15][c:16]2[n:17][cH:18][cH:19][cH:20][c:21]2[C:22]([CH3:23])([CH3:24])[c:25]2[cH:26][cH:27][c:28]([F:31])[cH:29][cH:30]2)[CH2:39][c:36]2[c:35]([CH3:41])[cH:34][c:33]([Cl:32])[cH:38][n:37]2)[CH2:12][CH2:13]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-2a6264f2112c4093835e0ff464f0309b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…