Acetonitrile → 8-[(6-Bromopyridin-2-yl)-(tert-butyldimethylsiloxy)methyl]-10-methoxymethyl-10H-pyrazino[2,3-b][1,4]benzothiazine

Reaction equation

[C:27]([CH3:28])([CH3:29])([CH3:30])[Si:31]([N:32]([CH3:33])[C:34](=[O:35])[C:36]([F:37])([F:38])[F:39])([CH3:40])[CH3:41].[CH3:1][O:2][CH2:3][N:4]1[c:5]2[c:6]([n:23][cH:24][cH:25][n:26]2)[S:7][c:8]2[c:9]1[cH:10][c:11]([CH:14]([OH:15])[c:16]1[n:17][c:18]([Br:22])[cH:19][cH:20][cH:21]1)[cH:12][cH:13]2.[CH3:42][C:43]#[N:44]>>[CH3:1][O:2][CH2:3][N:4]1[c:5]2[c:6]([n:23][cH:24][cH:25][n:26]2)[S:7][c:8]2[c:9]1[cH:10][c:11]([CH:14]([O:15][Si:31]([C:27]([CH3:28])([CH3:29])[CH3:30])([CH3:40])[CH3:41])[c:16]1[n:17][c:18]([Br:22])[cH:19][cH:20][cH:21]1)[cH:12][cH:13]2