Ethanol → 1,1-Dimethylethyl 4-[(2-amino-4-chloro-5-methoxyphenyl)amino]-1-piperidinecarboxylate

Reaction equation

[CH3:1][O:2][c:3]1[c:4]([Cl:26])[cH:5][c:6]([N+:23]([O-:24])=[O:25])[c:7]([NH:9][CH:10]2[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]2)[cH:8]1.[CH3:30][CH2:31][OH:32].[NH2:28][NH2:29].[OH2:27]>>[CH3:1][O:2][c:3]1[c:4]([Cl:26])[cH:5][c:6]([NH2:23])[c:7]([NH:9][CH:10]2[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]2)[cH:8]1

Participants

Reactant 4

HCID 702Ethanol

HCID 962Water

HCID 9321Hydrazine

HCID 598501431,1-Dimethylethyl 4-[(5-methoxy-4-chloro-2-nitrophenyl)amino]-piperidinecarboxylate

Product 1

HCID 598502131,1-Dimethylethyl 4-[(2-amino-4-chloro-5-methoxyphenyl)amino]-1-piperidinecarboxylate

Sources & evidence

ORD record: ord-4b9dbcc01adf45f38a577956b48d2166
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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