Methanol → [5-(4-Bromo-2-hydroxymethyl-phenoxy)-2-chloro-phenyl]-acetic acid ethyl ester

Reaction equation

[BH4-:24].[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][c:6]1[c:7]([Cl:22])[cH:8][cH:9][c:10]([O:12][c:13]2[c:14]([CH:20]=[O:21])[cH:15][c:16]([Br:19])[cH:17][cH:18]2)[cH:11]1)=[O:23].[CH3:26][OH:27].[Na+:25]>>[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][c:6]1[c:7]([Cl:22])[cH:8][cH:9][c:10]([O:12][c:13]2[c:14]([CH2:20][OH:21])[cH:15][c:16]([Br:19])[cH:17][cH:18]2)[cH:11]1)=[O:23]

Participants

Reactant 4

HCID 887Methanol

HCID 923Sodium Ion

HCID 28123Borohydride

HCID 58237600[5-(4-Bromo-2-formyl-phenoxy)-2-chloro-phenyl]-acetic acid ethyl ester

Product 1

HCID 58237446[5-(4-Bromo-2-hydroxymethyl-phenoxy)-2-chloro-phenyl]-acetic acid ethyl ester

Sources & evidence

ORD record: ord-07cdfb9ccc694f7ebfb67abda3a085bb
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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